PROTEOMIC INSIGHTS INTO EXTRACELLULAR VESICLES IN ALS FOR THERAPEUTIC POTENTIAL OF ROPINIROLE AND BIOMARKER DISCOVERY

Proteomic insights into extracellular vesicles in ALS for therapeutic potential of Ropinirole and biomarker discovery

Abstract Background Extracellular vesicles (EVs) hold the potential for elucidating the pathogenesis of amyotrophic lateral sclerosis (ALS) and serve as biomarkers.Notably, the comparative and longitudinal alterations in the protein profiles of COOKIE KETO EVs in serum (sEVs) and cerebrospinal fluid (CSF; cEVs) of sporadic ALS (SALS) patients remai

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Discovering Host Genes Involved in the Infection by the Tomato Yellow Leaf Curl Virus Complex and in the Establishment of Resistance to the Virus Using Tobacco Rattle Virus-based Post Transcriptional Gene Silencing

The development of high-throughput technologies allows for evaluating gene expression at the whole-genome level.Together with proteomic and metabolomic studies, these analyses have resulted in the identification of plant genes whose function or expression is altered as a consequence of pathogen attacks.Members of the Tomato yellow leaf curl virus (

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